Research progress on mechanism of autophagy in intestinal mucosal barrier function
- VernacularTitle:自噬在肠黏膜屏障功能作用机制的研究进展
- Author:
Binbin WANG
;
Chengfeng WU
;
Fangxin ZHANG
- Keywords:
autophagy;
intestinal mucosal barrier;
intestinal epithelial cells
- From:
Basic & Clinical Medicine
2017;37(3):405-409
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a biological process in which cells maintain homeostasis through degradation of cytoplasmic macromolecules and damaged organelles by membrane vesicle structure .Autophagy plays a critical role in maintai-ning survival of intestinal epithelial cells during intestinal mucosal barrier dysfunction .A negative regulator of auto-phagy may lead to intestinal inflammation and tumorigenesis .
