The progress in metabolomics in respiratory disease
10.11958/20161237
- VernacularTitle:代谢组学在呼吸系统疾病中的研究进展
- Author:
Jun HU
;
Guisheng YI
- Keywords:
respiratory tract diseases;
biological markers;
laboratory techniques and procedures;
diagnosis;
differential;
review;
metabolomics;
treatment
- From:
Tianjin Medical Journal
2017;45(3):324-328
- CountryChina
- Language:Chinese
-
Abstract:
When a series of omics technologies such as genomics, epigenomics and proteomics are proposed, the concept of metabolomics occurs. Metabolomics is a top-down system biology approach, which analyzes endogenous metabolites by using high throughput, high resolution and high sensitivity based on metabolic analysis platform. By identifying characteristic biomarkers and analyzing the biomarkers of metabolic pathway, it will provide a new way for the diagnosis and treatment of diseases. Therefore, it is more and more widely used in bronchial asthma, chronic obstructive pulmonary disease, pulmonary cystic fibrosis, acute respiratory distress syndrome, pulmonary tuberculosis, lung cancer and other respiratory diseases. In this paper, the application of metabolome analysis in respiratory disease of recent years has been briefly reviewed.
