Clinical effect of inhalation of terbutaline and budesonide combined with oral Xiaoerkechuanling granules in the treatment of infantile asthma
10.3760/cma.j.issn.1008-6706.2017.05.018
- VernacularTitle:雾化吸入特布他林和布地奈德联合服用小儿咳喘灵颗粒治疗小儿哮喘的临床效果研究
- Author:
Zhongxiang LIN
- Keywords:
Asthma;
Xiaoerkechuanning granule;
Terbutaline;
Budesonide
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(5):710-713
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of inhalation of terbutaline,budesonide combined with Xiaoerkechuanling granules in the treatment of infantile asthma.Methods 96 children with asthma were selected and randomly divided to observation group and control group.The two groups were given routine drug treatment,the control group was given sulfate inhalation terbutaline atomization liquid and budesonide suspension on the basis of conventional treatment.The observation group was given Xiaoerkechuanling granules on the basis of the control group. The two groups were treated for 7 days.The clinical curative effect of the two groups,the changes of lung function and adverse reactions were observed.Results After treatment,the total effective rate in the observation group was 93.80%,which in the control group was 75.00%,the difference between the two groups was statistically significant (χ2 =3.200,P <0.05).The FEV1 ,FEV1 and FEV /FEV1 of the observation group were (3.49 ±0.61)L,(2.54 ± 0.47)L,(93.33 ±8.46)%,which were significantly better than those of the control group[(2.79 ±0.52)L,(1.96 ± 0.43)L,(75.98 ±5.8)%],the differences between the two groups were statistically significant(t =6.050,6.308, 11.693,all P <0.05).The incidence rate of adverse reaction in the observation group was 12.60%,which in the control group was 10.50%,there was no statistically significant difference between the two groups (χ2 =0.051,P >0.05 ).Conclusion Inhalation of terbutaline,budesonide combined with Xiaoerkechuanling granules for the treatment of asthma in children can significantly improve the patients'pulmonary function,improve clinical curative effect,and it has less adverse reaction and great clinical value.
