Study on the effects of tonsillectomy and adenoidectomy on the body's immune function of preschool children
10.3760/cma.j.issn.1008-6706.2017.06.036
- VernacularTitle:学龄前儿童扁桃体和腺样体切除后对机体免疫功能影响的研究
- Author:
Yucai SUN
- Keywords:
Tonsil;
Adenoid;
Immune function;
Child,preschool;
Surgical operation
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(6):937-939
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of tonsillectomy and adenoidectomy on the body's immune function of preschool children.Methods Using paired comparison method,40 preschool children with OSAHS[aver-age age (4.5 ±1.2)years]were selected.The peripheral venous blood's white blood cells,neutrophils,lymphocytes, monocytes,immune active cells(total T lymphocytes and total B lymphocytes),immunoglobulin(IgA,IgG,IgM)and the content of C3 and C4 levels in the different periods (after 1 month,3 months )before and after tonsillectomy and adenoidectomy were detected.And the immune parameters of 20 healthy children with matched age were selected as control group,the analysis comparison was conducted.Results In preoperative and postoperative 1 month,3 months compared with the control group,the above immune parameters had no statistically significant differences (t =0.332, 0.212,0.336,0.415,0.579,1.295,0.874,1.143,1.296,1.058,1.261,all P >0.05).At postoperative 1 month, the immune active cells(total T lymphocytes and total B lymphocytes),immunoglobulin (IgA,IgG,IgM)and the content of C3 and C4 levels declined slightly compared with preoperation,but within the normal range,back to normal at postoperative 3 months.Conclusion Tonsillectomy and adenoidectomy will not suppress the development of preschool children's immune systems,and the resection is feasible.