Unusual Cutaneous Neutrophilic Infiltration in Myelodysplasia Syndrome : A Nuclear Segmentation Anomaly.
10.5021/ad.1998.10.4.270
- Author:
Seong Jin KIM
;
Jae Jeong SEO
;
Seung Chul LEE
;
Young Ho WON
- Publication Type:Case Report
- Keywords:
Myelodysplastic syndrome;
Neutrophilic dermatoses;
Nuclear segmentation anomaly;
Acute transformation
- MeSH:
Myelodysplastic Syndromes;
Neutrophils*;
Pyoderma Gangrenosum;
Skin Diseases;
Sweet Syndrome
- From:Annals of Dermatology
1998;10(4):270-273
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of myelodysplastic syndrome (MDS) with unique histopathological findings in which numerous infiltrated neutrophils exhibited nuclear segmentation anomalies. In comparison with well-described neutrophilic dermatoses of myelodysplastic syndrome such as Sweets syndrome and pyoderma gangrenosum, this case took a rapid and aggressive clinical course. We suggest that a nuclear segmentation anomaly, pseudo Pelger-Hiiet anomaly, is likely to reflect acute transformation of MDS and can be a poor prognostic marker.
