Comparison of the effect of different administration methods of carboprost tromethamine for the treatment of scar uterus with cesarean resection
10.3760/cma.j.issn.1008-6706.2017.05.033
- VernacularTitle:卡前列素氨丁三醇不同给药方式用于瘢痕子宫再次剖宫产术的疗效比较
- Author:
Juan WEN
- Keywords:
Cesarean section;
Carboprost Tromethamine;
Scar;
Uterus;
Postpartum hemorrhage
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(5):767-770
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical effect of different administration methods of carboprost tromethamine for the treatment of scar uterus with cesarean resection.Methods 120 cases of puerpera with uterine scar uterus and postpartum hemorrhage tendency were selected,and the history of cesarean section was once and more than once.According to the digital table,they were randomly divided into observation group(60 cases)and control group(60 cases),the observation group was divided into single carboprost tromethamine administration group(30 cases) and sub carboprost tromethamine administration group (30 cases).The clinical efficacy of the three groups were compared.Results In the observation group,the incidence rates of postpartum hemorrhage(13.33%,10.00%)were significantly lower than 28.33% in the control group(χ2 =10.844,6.822,all P <0.05).The incidence of postpartum hemorrhage of the single carboprost tromethamine administration group and sub carboprost tromethamine administration group(13.33% vs.10.00%)showed no statistically significant difference(χ2 =0.538,P >0.05).24h postpartum hemorrhage in the observation group[(263.11 ±137.04)mL,(359.98 ±212.35)mL]were significantly lower than those of the control group[(461.52 ±127.67)mL](t =5.795,2.247,all P <0.05).24h postpartum hemorrhage of the sub carboprost tromethamine administration group[(263.11 ±137.04)mL]was significantly less than that of the single carboprost tromethamine administration group[(359.98 ±212.35)mL,t =2.097,P <0.05].There was no statistically significant difference in the adverse reactions among the three groups(P >0.05).Conclusion Carbo-prost tromethamine can significantly reduce the bleeding rate of uterine scar again after cesarean section,sub carbo-prost tromethamine administration can significantly reduce the amount of bleeding in postoperative 24h,it is worth popularizing in clinical.
