Influence of hyperglycemia on hospitalization and follow-up prognosis in emergency PCI patients

Hongbo Dang; Jun Qian; Jianhua Mao; Ning Zhou; He WU; Yongqiang MA

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Influence of hyperglycemia on hospitalization and follow-up prognosis in emergency PCI patients

VernacularTitle:高血糖对急诊 PCI 患者住院与随访预后的影响
Author: Hongbo DANG ; Jun QIAN ; Jianhua MAO ; Ning ZHOU ; He WU ; Yongqiang MA
Keywords: Hyperglycemia; Myocardial infarction; Angioplasty,balloon,coronary; Percutaneous coronary interventions
From: Chinese Journal of cardiovascular Rehabilitation Medicine 2017;26(1):63-67
CountryChina
Language:Chinese
Abstract: Objective:To explore influence of hyperglycemia on hospitalization and follow‐up prognosis in patients with acute ST elevation myocardial infarction (STEMI ) undergoing direct percutaneous coronary intervention (PCI) .Methods :A total of 218 patients ,who were diagnosed as STEMI and received emergency PCI within 12h af‐ter onset from our hospital ,were enrolled .According to blood glucose level at hospitalization and OGTT results , they were divided into normal blood glucose (NBG) group (n= 108) ,hyperglycemia group (n= 60) and diabetes mellitus (DM) group (n=50) .Cardiac function indexes were evaluated ;Logistic regression analysis was used to an‐alyze influencing factors for mortality in these patients .Results:Compared with NBG group , the in‐hospital mortal‐ity was significant rise (1.9% vs .10.0% ) in DM group ;there were significant rise in percentages of ≥double‐vessel coronary disease (41.2% vs .68.8% vs .66.7% ) and ≥2 stents implanted (14.72% vs .50.0% vs .55.6% ) in women in hyperglycemia group and DM group (P<0.05 or <0.01);Multi‐factor Logistic regression analysis indi‐cated that Killip class ,NT‐proBNP ,number of diseased vessels and body mass index were independent risk factors of in‐hospital mortality of these patients (OR=1.012~5.923 ,P<0.05 all) ,and female was a strong independent risk factor for in‐hospital mortality and mortality within one‐year follow‐up (OR=20.376 ,7.227 ,P<0.01 both) .Con‐clusion:The mortality significantly rises in STEMI patients undergoing emergency PCI complicated with hyperglyce‐mia ,especially in female patients .