Age-specific Reference Ranges for Prostate-specific Antigen from a Community-based Study.
- Author:
Jun Hyuk HONG
1
;
Tae Gyu CHUNG
;
Minsu PARK
;
Jinhyung LEE
;
Taehyo KIM
;
Jin Soo CHUNG
;
Moo Song LEE
;
Han Jong AHN
Author Information
1. Department of Urology, University of Ulsan College of Medicine, Ulsan, Korea.
- Publication Type:Original Article
- Keywords:
Prostate-specific antigen;
Age-specific reference range;
Korean Prostatic neoplasms
- MeSH:
Digital Rectal Examination;
Humans;
Jeollabuk-do;
Korea;
Male;
Prostate-Specific Antigen*;
Prostatic Neoplasms;
Reference Values*
- From:Korean Journal of Urology
1998;39(11):1065-1069
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To analyze the relationship of age to serum prostate-specific antigen (PSA) levels among Koreans without clinically evident prostate cancer in a community-based study. MATERIALS AND METHOD: A total of 375 healthy men aged 50 to 79, residing in the small farming villages of Jeong-Eup county, Korea were examined with serum PSA(Hybritech Tandem-R) and digital rectal examination. One case of patient with prostate cancer was excluded. RESULTS: The serum PSA concentration is correlated with patient age(In PSA=-1.56+0.0257 x Age, r=0.32, p-value<0.0001). The recommended age-specific reference ranges of serum PSA(95th percentile) for men aged 50-59 years is 0-2.80ng/m1; for 60-69 years,0-3.56ng/m1; and for 70-79 years, 0-4.57ng/m1. CONCLUSIONS: The serum PSA concentration is correlated with patient age in Korean men and the age-specific PSA reference ranges for Korean are lower than those for Caucasian.
