Recognition of macrophage activation syndrome
10.3760/cma.j.issn.2095-428X.2017.03.018
- VernacularTitle:巨噬细胞活化综合征的再认识
- Author:
Huihui MA
;
Haiguo YU
- Keywords:
Macrophage activation syndrome;
Hemophagocytic lymphohistiocytosis;
Systemic onset juvenile idiopathic arthritis;
Recognition
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(3):238-240
- CountryChina
- Language:Chinese
-
Abstract:
Macrophage activation syndrome (MAS)is a serious potentially life -threatening complication seen primarily in patients with systemic onset juvenile idiopathic arthritis (sJIA).Clinical symptoms include persis-tent fever,liver and spleen lymph node enlargement,cytopenia,hyperferritinemia,hypofibrinogenemia,hypertriglyceri-demia,coagulation disorders,and hemophagocytosis can be seen in the bone marrow.This article summarizes the characteristics of MAS occurring in the context of sJIA and discuss the recent advances in classification systems and management.
