Effect of Kangfuxin Liquidon on gingiva groove liquid IL-1β, PGE2, sICAM-1in fixed orthodontic patients with gingivitis
10.3969/j.issn.1005-1678.2017.01.020
- VernacularTitle:康复新液对固定正畸牙龈炎患者龈沟液IL-1β、PGE2及sICAM-1的影响
- Author:
Rui CHEN
;
Jin HE
- Keywords:
fixed orthodontic patients with gingivitis;
Kangfuxin Liquidon;
interleukin-1β;
prostaglandin E2;
soluble adhesion molecule-1
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):78-80
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of Kangfuxin Liquidon on gingiva groove liquid interleukin 1β(IL-1β), prostaglandin E2 (PGE2), soluble adhesion molecule-1 (sICAM)in fixed orthodontic patients with gingivitis. Methods 96 cases of patients with fixed orthodontic gingivitis consult the draw method were divided into control group and experimental group, 48 cases in each group. The control group were treatedby gums clean, experimental group based on the control group were treattedby Kangfuxin Liquidon. The IL-1β, PGE2, sICAM-1 levels, periodontal status, the grade of swelling and pain, the clinical curative effect were compared between two groups. Results After treatment, the IL-1β, PGE2, sICAM levels of experimental group were lower than the control group (10.54±1.41) ng/L vs.(11.85±1.71)ng/L, (284.62±35.21) ng/L vs.(314.65±39.48)ng/L, (150.49±18.11) μg/L vs.(162.83±20.26) μg/L,the differences were statistically significant (P<0.05).The periodontal status, swelling and pain grading ofexperimental group were better than control group (P<0.05). Theeffective rate of experimental group was higher than the control group (95.83%vs.79.17%) (P<0.05). Conclusion Kangfuxin Liquidon can reduce fixed orthodontic patients with gingivitis gingiva groove IL-1β, PGE2, sICAM-1 levels, improve the periodontal status, relieve swelling and pain, improve the clinical curative effect.
