Effect of compound betamethasone injection combined with radiation on keloid in frontal facial region
10.3969/j.issn.1005-1678.2017.01.049
- VernacularTitle:复方倍他米松注射液联合放射对额面部瘢痕疙瘩患者的治疗效果
- Author:
Haifeng ZENG
;
Yu JI
;
Sheng YAN
- Keywords:
compound betamethasone injection;
eradiotherapy;
facies frontalis department;
keloid
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):169-171
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analysis the effect of compound betamethasone injection combined with radiation on keloid in frontal facial region. Methods 60 cases of keloid patients in zhejiangprovincial people's hospital from January 2014 to January 2016 were selected,all patients were treated with surgery,the patients were randomly divided into observation group and control group,30 cases in each group,radiotherapy was used in the control group,the observation group was treated with local injection of compound betamethasone on the basis of the control group,the therapeutic effects, pain scores, adverse reactions and complications were compared between the two groups. Results The recurrence rate of the observation group was 3.33% which was significantly lower than that of the control group 10%,the improvement rate of the observation group 93.33% was significantly higher than the control group 80%,the difference was statistically significant (P<0.05).one,two and three months after operation,the pain scores in the observation group were significantly lower than those in the control group at the same time point,the difference was statistically significant (P<0.05).The adverse reaction rate was 6.66% (2/30) in the observation group and 23.33% (7/30) in the control group, there was no significant difference between the two groups.The incidences of skin sag, pigmentation, incision delayed union and telangiectasia in the observation group were significantly lower than those in the control group (P<0.05). Conclusion Compound betamethasone injection combined with radiation on the frontal facial keloid patients with significant effect,can significantly reduce the recurrence rate,improve the rate of improvement,reduce pain and complications in patients.
