Standardized management of thalassemia
10.3760/cma.j.issn.2095-428X.2017.03.002
- VernacularTitle:地中海贫血的规范化管理
- Author:
Zhixu HE
;
Jiao JIN
- Keywords:
Thalassemia;
Transfusion;
Health education;
Genetic intervention
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(3):168-172
- CountryChina
- Language:Chinese
-
Abstract:
Thalassemia is inherited hemolytic anemia caused by globin production disorder,clinically known as beta thalassemia and alpha thalassemia resulted from beta and alpha chain synthesis disorder.Significant anemic clinical manifestations are observed in intermediate -level and severe -level patients with the 2 types of anemia, affecting greatly the growth and life quality of children patients who need blood transfusion to stay alive.The incidence rate of thalassemia is as high as 7% -20% in South China,so the prevention and standaridized treatment of thalasse-mia and the management over target population draw more attention.This paper is a review on the latest development of blood transfusion,chelation therapy,health education,birth intervention for thalassemia.
