Effect of fibroblast growth factor on extraction of tooth in type 2 diabetic patients
10.3969/j.issn.1005-1678.2017.01.035
- VernacularTitle:成纤维细胞生长因子对2型糖尿病患者拔牙并发感染的预防作用
- Author:
Ligang ZHANG
;
Lizhen YING
;
Bin ZHANG
;
Yunyan KE
- Keywords:
fibroblast growth factor;
extraction;
infection;
type 2 diabetes mellitus
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):126-128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the preventive effect of fibroblast growth factor on infection after tooth extraction among type 2 diabetes mellitus patients. Methods 76 patients with infection prevention were treated with basic fibroblast growth factor, and 90 patients in the control group(n= 324). The intervention group was treated with basic fibroblast growth factor and treated with recombinant bovine basic fibroblast growth factor gel. The routine treatment group was treated with routine rinsing liquid for disinfection to prevent infection. Follow-up observation of infection after 1 week. Results In the group of basic fibroblast growth factor, the infectious rate was 2.63%, which was not significantly lower than that of the control group. The level of white blood cells in the group treated with basic fibroblast factor was (6.67±1.08)×109/L, which was significantly lower than that of the control group. The CRP level was (90.33±12.95) mg/L, which was significantly lower than that of the control group Group level (P<0.05). The incidence of fibroblast infection was 2.7% in men and 6.38% in control group. Although there was no significant difference between the two groups, the difference in the total WBC count and CRP level between the two groups was significant different (P<0.05). The group which use of basic fibroblast growth factor, the total white blood cell count and CRP level of the infection prevention intervention group were significantly lower than the control group (P<0.05). Similar results were found in women. Conclusion Fibroblast growth factor can be used to prevent postoperative infection, and achieve satisfactory results.
