Clinical effect of Kang Shuling gel on the inflammatory factors in Ⅱ degree burns
10.3969/j.issn.1005-1678.2017.01.039
- VernacularTitle:慷舒灵凝胶对Ⅱ度烧伤患者的疗效及对血清炎症因子的影响
- Author:
Qiang HU
;
Shuang SUI
;
Guodong WANG
;
Limin YAO
- Keywords:
Ⅱ degree burns;
Kang Shuling gel;
curative effect;
inflammatory factors
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(1):139-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Kang Shueling gel on the degree of inflammation in the patients with Ⅱ degree burns. Methods 86 patients with Ⅱ degree burns from July 2014 to July 2016 in our hospital were divided into the control group and the experimental group by lottery method with 43 cases in each group. The control group was treated with silver sulfadiazine, the experimental group was treated with Kang Shuling gel, the two groups of clinical curative efficacy, inflammatory factors, visual analogue scale (VAS), wound healing rate and wound healing time, wound infection rate and adverse drug reactions were compared. Results After treatment, the total effective rate of the experimental group was 95.34% higher than that of the control group 72.09%, the difference was statistically significant (P<0.05). The tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6) levels of the experimental group was lower than the control group, the difference was statistically significant (P<0.05). The VAS of the experimental group was lower than the control group, the difference was statistically significant (P<0.05).The wound healing rate of the experimental group was higher than that of the control group on the seventh day and the fourteenth day, and the wound healing time was better than that of the control group, the difference was statistically significant (P<0.05). The wound infection rate of the experimental group was lower than that of the control group (P<0.05). There was no significant difference in adverse drug reactions between the two groups. Conclusion The curative effect of Kang Shuling gel on the treatment of Ⅱ degree burns patients worthy of affirmation, could reduce serum inflammatory factors level.
