Progress of Dystrophin Isoform Dp140 (review)
10.3969/j.issn.1006-9771.2017.03.012
- VernacularTitle:抗肌萎缩蛋白亚型Dp140的研究进展
- Author:
Yayun NIU
;
Yuru DONG
;
Shiwen WU
- Keywords:
Duchenne muscular dystrophy;
dystrophin;
Dp140;
review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2017;23(3):308-310
- CountryChina
- Language:Chinese
-
Abstract:
Duchenne muscular dystrophy is the most prevalent muscular dystrophy caused by dystrophin gene mutations. In the central nervous systerm, there are at least six dystrophin isoforms, in which Dp140 is closely associated with cognitive impairment. This paper re-viewed the discovery, structure, gene location, detection methods and function of Dp140.
