Progress of relationship between phosphatase of regeneration liver-3 and tumors
10.3760/cma.j.issn.1006-9801.2017.03.017
- VernacularTitle:肝再生磷酸酶3与肿瘤相关性的研究进展
- Author:
Xiujun SONG
- Keywords:
Phosphatase of regeneration liver-3;
Neoplasm metastasis;
Prognosis
- From:
Cancer Research and Clinic
2017;29(3):208-211
- CountryChina
- Language:Chinese
-
Abstract:
Phosphatase of regenerating liver-3 (PRL-3) is a kind of non-transmembrane protein-tyrosine phosphatase, characterized by its promotion of cell proliferation, migration and invasion. It is highly expressed in many tumors and has a close correlation with tumorigenesis, metastasis and prognosis. With the further research in recently years, more and more studies have suggested that PRL-3 has a wide applicative prospect in clinic, serving as a important clinical biological marker to predict tumor metastasis and prognosis. This paper will review the structure of PRL-3, mechanism and relationship between PRL-3 and tumors.
