Optimization of the Water Extraction Technology of Xiaokeantangfang by Orthogonal Tests
- VernacularTitle:正交试验优化消渴安糖方的水提取工艺
- Author:
Yuanlan OU
;
Guoman DAI
;
Shasha WEI
;
Xiuneng TANG
- Keywords:
Xiaokeantangfang;
Astragaloside A;
Extraction technology;
Orthogonal tests
- From:
China Pharmacist
2017;20(3):479-482
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the water extraction technology of Xiaokeantangfang. Methods: The extraction technology of Xiaokeantangfang was optimized by orthogonal design with the content of astragaloside A and the extract yield as the indices and the a-mount of added water,extraction time and extraction times as the influencing factors,and the results were verified. Results:The amount of added water had significant effect on the content of astragaloside A(P<0. 05). The optimal extraction technology was as follows:12-fold amount of added water,extracting for 3 times with 0. 5 hour per time. The average extract yield was 38. 33%(RSD=1. 22%,n=3), and the average content of astragaloside A was 0. 0828 mg·g-1 for 3 batches of samples in the validation tests(RSD=3. 37%, n=3). Conclusion:The optimal water extraction technology of Xiaokeantangfang is stable and feasible, which can provide experimen-tal basis for the oral preparation of Xiaokeantangfang.
