Acute Gouty Arthritis Presented after Pyrazinamide Treatment in a Patient with Chronic Renal Insufficiency.
- Author:
Ki Hoon HUR
1
;
Sun Ae YOON
;
Young Ok KIM
;
Kang Woo LEE
;
Ji Hyun JUNG
;
Chan Ran YOU
;
Sun Wha SONG
;
Kyung Soo PARK
;
Kwan Hyung KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. cmckyo@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Acute gouty arthritis;
Tuberculosis;
Pyrazinamide;
Hyperuricemia;
Renal insufficiency
- MeSH:
Aged;
Arthralgia;
Arthritis, Gouty*;
Colchicine;
Female;
Humans;
Hyperuricemia;
Joints;
Metatarsophalangeal Joint;
Needles;
Pyrazinamide*;
Renal Insufficiency;
Renal Insufficiency, Chronic*;
Tuberculosis;
Uric Acid
- From:Korean Journal of Nephrology
2003;22(5):586-589
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although arthralgia with or without hyperuricemia commonly occurs in a patient receiving antituberculous treatment including pyrazinamide, acute gouty arthritis is rarely reported. Here we report a case of acute gouty arthritis presented after antituberculous treatment in a patient with asymptomatic hyperuricemia and mild renal insufficiency. A 76-year-old woman complained sudden onset of painful swelling in both first metatarsophalangeal joints 9 weeks after antituberculous treatment. She had hypertensive nephropathy with mild renal insufficiency and asymptomatic hyperuricemia for 8 years. Needle aspiration of the joint fluid demonstrated needle-shaped strongly negative birefringent monosodium urate crystal. The painful swelling improved with steroid and colchicine.
