Neutralization of Lecithin and Polysorbate-80 in Antibacterial Activity of Traditional Chinese Medicine Preparations
- VernacularTitle:卵磷脂和聚山梨酯-80联用在中药制剂抑菌活性中的中和作用
- Author:
Jun JI
;
Tingting LIU
;
Mengmeng NIU
;
Zunwen WANG
- Keywords:
Lecithin;
Polysorbate-80;
Microbial limit test;
Applicability test;
Neutralization;
Traditional Chinese medicine prep-arations
- From:
China Pharmacist
2017;20(3):586-588
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the neutralization of lecithin and polysorbate-80 in antibacterial activity of oral solid tradition-al Chinese medicine preparations without Chinese medicinal herb powder. Methods:According to the requirements in Chinese Pharma-copeia (2015 edition), the applicability of microbial counting method was tested in the diluent containing lecithin and polysorbate-80 and the conventional diluent, respectively, and the results were compared. Results: The recovery results of applicability of microbial counting method using neutralizers (lecithin and polysorbate-80) conformed to the standard of Chinese pharmacopoeia (2015 edition). Conclusion:The combination of lecithin and polysorbate-80 has notable neutralization in antibacterial activity of oral solid traditional Chinese medicine preparations without Chinese medicinal herb powder.
