A Case of Acute Myocardial Infarction Due to Coronary Artery Thrombosis During the Relapse of Nephrotic Syndrome.
- Author:
Eun Ki PAIK
1
;
Jeong Woo PARK
;
Young Nam KIM
;
In Sung MOON
;
Hyun Hee LEE
;
Joon Seung LEE
;
Woo Kyung CHUNG
;
Eak Kyun SHIN
;
Moon Hyang PARK
;
Jong Ho LEE
Author Information
1. Department of Internal Medicine, Gacheon Medical School, Incheon, Korea. nephlee@ghil.com
- Publication Type:Case Report
- Keywords:
Nephrotic syndrome;
Acute myocardial infarction;
Intracoronary thrombosis;
Hypercoagulable state
- MeSH:
Adult;
Arteries;
Coronary Angiography;
Coronary Vessels*;
Edema;
Emergencies;
Humans;
Male;
Myocardial Infarction*;
Nephrosis, Lipoid;
Nephrotic Syndrome*;
Proteinuria;
Recurrence*;
Thrombolytic Therapy;
Thrombosis*
- From:Korean Journal of Nephrology
2003;22(5):597-601
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vascular thrombosis is one of the most serious complications in patients with nephrotic syndrome, but thrombosis occurs mainly in venous system. Arterial thrombosis is much less common and coronary artery thrombosis is rarely reported worldwide. We experienced a case of an acute myocardial infarction due to coronary artery thrombosis in a young male with minimal change disease during nephrotic relapse. This 35 year-old male was diagnosed to have minimal change nephrotic syndrome 15 years before admission. Two days before admission, he was found to have heavy proteinuria and edema which led to impression of relapse of nephrotic syndrome. Acute myocardial infarction was developed one day before admission and emergency thrombolytic therapy was performed. After admission, coronary angiography was performed and multiple thrombi were identified in distal left anterior descending artery without marked atherosclerotic changes. The formation of intracoronary thrombi in this patient appeared to be due to the hypercoagulable state associated with the relapse of nephrotic syndrome.
