Review and Meta-analysis of the ω-3 polyunsaturated fatly acid for cancer cechexia treatment
10.16151/j.1007-810x.2017.01.008
- VernacularTitle:ω-3多不饱和脂肪酸治疗癌性恶病质系统评价及荟萃分析
- Author:
Shiwei LI
;
Huaixing MA
;
Suyi LI
- Keywords:
PUFA;
Cancer cachexia;
Systematic evaluation
- From:
Parenteral & Enteral Nutrition
2017;24(1):28-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical value of PUFA in the treatment of cancer cachexia,meta-analysis and systematic evaluation of literature was applied.Methods:According to the inclusion criteria,PubMed/MEDLINE,EMBASE and the Cochrane Central Register of Controlled TriMs for randomized controlled trims that compared PUFA treatments with placebo or no treatment in cancer cachexia were searched.Outcomes of interest were effects on weight,appetite,the level of CRP and IL-6,the composition of lean body mass and the quality of life.Results:Finally,16 articles were included in the analysis,which reported appetite (6 papers),C-reactive protein (9 papers),IL-6 (5 papers),lean tissue weight (7 papers) and quality of life assessment (7 papers),respectively.Conclusion:PUFAs for the treatment of cancer cachexia plays an irreplaceable role.The body weight,appetite,inflammation index and quality of life can be significantly improved,and the patients can tolerated the addition of PUFA during the treatment.
