Research progress of in vitro maturation of Beagle dog oocytes
10.3969/j.issn.1005-4847.2017.01.020
- VernacularTitle:Beagle犬卵母细胞体外成熟研究进展
- Author:
Minhua HU
;
Zhidong ZHOU
;
Qingchun NI
;
Yunzhong LIU
- Keywords:
Beagle dogs;
Disease model;
Ooocytes;
in vitro maturation
- From:
Acta Laboratorium Animalis Scientia Sinica
2017;25(1):107-110
- CountryChina
- Language:Chinese
-
Abstract:
Sufficient embryos are needed for the preservation of Beagle dogs germplasm resources and the prepara-tion of gene?modified human disease animal models. Up to now, the induced ovulation technique has no effect on dogs,it is hard to obtain mature oocytes in vivo, although the scientists try a lot in many aspects, but still could not make a break?through. The in vitro maturation rate is too low to support the preservation of germplasm resources, application in gene?modified disease models and biomedical research. Aiming to provide useful information on breakthrough in dog oocytes mat?uration, this review will summarize the effect of different age and reproductive stage,different morphology and size of the oo?cytes and lipid droplet on the in vitro maturation of dog oocytes.