Analysis for Renal Function Related Influencing Factors on 8-year Survival in Chronic Heart Failure Patients
10.3969/j.issn.1000-3614.2017.03.009
- VernacularTitle:慢性心力衰竭患者8年生存的肾功能相关指标影响因素分析
- Author:
Liangdong XU
;
Xiaojun WANG
;
Yidan WANG
;
Xiao CONG
;
Xiaoqian SHEN
;
Hesheng HU
;
Suhua YAN
;
Enkui HAO
- Keywords:
Heart Failure;
Renal function test;
Survival rate
- From:
Chinese Circulation Journal
2017;32(3):245-248
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To assess blood levels of renal function related influencing factors with baseline clinical parameters for predicting the risk of 8-year survival in patients with chronic heart failure (CHF). Methods: A total of 293 CHF patients admitted in our hospital from 2006-07 to 2009-11 were enrolled. The patients were followed-up until 2014-6-30, the end point was death. According to followed-up results, they were divided into 2 groups: Survival group,n=107 and Death group,n=186. All patients received routine renal function and electrolytes examination including blood levels of urea nitrogen, creatinine, uric acid, sodium, potassium, chloride, calcium, anion gap and phosphorus; GFR was calculated by MDRD formula. Baseline clinical parameters as left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) were measured by echocardiography; blood pressure (BP) and heart rate (HR) were recorded. The risk factors for 8-year survival in CHF patients were analyzed. Results: Compared with Survival group, Death group had increased LVEDD, urea nitrogen, creatinine and uric acid, while decreased LVEF, HR, GFR, blood sodium and calcium, allP<0.05. Univariate analysis indicated that LVEDD, LVEF, GFR, urea nitrogen, creatinine, uric acid, blood sodium, calcium and phosphorus had the better predictive value for the risk of 8-year survival in CHF patients, allP<0.05. Multivariate analysis presented that LVEDD, GFR and blood sodium had the highest predictive value for the risk of 8-year survival, allP<0.001; the next one was blood calcium,P<0.01. Conclusion: LVEDD, GFR, blood sodium and calcium were the independent predictors for the risk of 8-year survival in CHF patients.
