Comparison for Blood Levels of NT-proBNP and Uric Acid in Patients With Pulmonary Thromboembolism and Chronic Heart Failure

VernacularTitle:N末端B型利钠肽原和尿酸水平在肺动脉血栓栓塞症和慢性心力衰竭的比较
Author: Mingjie LIU ; Xin CUI ; Cheng YANG ; Qi CAO ; Dezhi LI ; Ling ZHU
Keywords: Pulmonary thromboembolism; Heart failure; NT-proBNP; Uric acid
From: Chinese Circulation Journal 2017;32(3):249-252
CountryChina
Language:Chinese
Abstract: Objective: To compare blood levels of NT-proBNP and uric acid (UA) in patients with pulmonary thromboembolism (PTE) and chronic heart failure (CHF). Methods: A prospective research was conducted in 288 acute dyspnea patients treated in our hospital from 2010-06 to 2015-05. The patients were divided into 2 groups based on clinical diagnosis: PTE group,n=107 and CHF group, n=181. Blood levels of NT-proBNP and UA were examined in all patients, statistical analysis was performed by SPSS 17.0 software, independent samplet test or variance analysis were used to make comparison between 2 groups. Results: There were more male patients as 64/107 (59.8%) in PTE group and 103/181 (56.9%) in CHF group. Compared with CHF group, PTE group had the lower blood levels of NT-proBNP (2421.7±1678.1) pg/ml vs (6964.3±3873.1) pg/ml and UA (340.6±121.3) μmol/L vs (492.1±166.2) μmol/L, allP<0.01. Conclusion: In our research, blood levels of NT-proBNP and UA were lower in PTE patients than CHF patients; with general background, such phenomenon might be helpful to distinguish PTE and CHF in acute dyspnea patients in clinical practice.