Advances in the research of genome-wide association studies on healthy adult height and missing heritability
10.13618/j.issn.1001-5728.2017.01.010
- VernacularTitle:健康成年人身高全基因组关联及遗传性缺失研究进展
- Author:
Huiyong JIAO
;
Wenting ZHAO
;
Caixia LI
;
Yanmei HUANG
;
Jian YE
- Keywords:
forensic biological evidence;
height;
genome-wide association studies;
gene;
heritability
- From:
Chinese Journal of Forensic Medicine
2017;32(1):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Human height, a complex trait with over 80% heritability, is determined by genetic and environment factors. Currently, a certain amount of specific variants about human height have been found, especially with the widely used of genome-wide association studies (GWAS) in genetics research, making it a great progress for the discovering of height associated genes. However, single nucleotide polymorphisms (SNPs) found by GWAS can only explain a minority of the heritable. This article reviews the progress of GWAS about height associated genes and missing heritability domestic and overseas.
