The pilot study of the phasing method for STR haplotypes
10.13618/j.issn.1001-5728.2017.01.002
- VernacularTitle:STR基因座单倍型的推断方法初探
- Author:
Yinming ZHANG
;
Danyuan YU
;
Ying WANG
;
Yang YANG
;
Ran LI
;
Ling HONG
;
Zhibo WAN
;
Hongyu SUN
- Keywords:
forensic biological evidence;
short tandem repeat;
linkage disequilibrium;
haplotype phasing
- From:
Chinese Journal of Forensic Medicine
2017;32(1):5-8
- CountryChina
- Language:Chinese
-
Abstract:
Referring to the statistical model for the SNP haplotype phasing which was based on the allele frequencies and advised by Browning SR, we investigated and deduced the phasing method of STR haplotype with linkage disequilibrium inpaternity testing preliminarily. Haplotype phasing of two X-STRs in linkage disequilibrium were illustrated. This method provides an idea for the haplotype phasing of STR markers, which is helpful for interpreting the typing results of STR more scientifically and accurately.
