Epidemiology status of some new emerging Cryptosporidium species and genotypes in humans
10.3969/j.issn.1002-2694.2017.02.011
- VernacularTitle:几种新现人体隐孢子虫种和基因型流行现状
- Author:
Ziyin YANG
;
Jianping CAO
;
Yujuan SHEN
;
Aiqin LIU
- Keywords:
Cryptosporidium;
cryptosporidiosis;
molecular epidemiology;
humans
- From:
Chinese Journal of Zoonoses
2017;33(2):148-155
- CountryChina
- Language:Chinese
-
Abstract:
Cryptosporidium spp.are protozoan parasites that infect the epithelial cells of the gstrointestinal tract of hosts.In humans,cryptosporidiosis is usually a self-limiting infection in immunocompetent individuals,but severe diarrhea and dissemination to extra-intestinal sites can occur in high-risk individuals,such as the very young,the elderly,immunedeficiency individuals,particularly in HIV-positive patients.So far,molecular epidemiological data have confirmed the presence of 30 species and over 40 genotypes with genus Cryptosporidium,with 21 species and genotypes being found in humans.The majority of human cryptosporidiosis cases are responsible for C.hominis and C.parvum.Human cases caused by C.meleagridis,C.ubiquitum,C.felis and C.canis have been increasing.Besides that,with data accumulation of molecular epidemiology of human cryptosporidiosis,some more Cryptosporidium species and genotypes were newly identified in humans.This paper mainly reviews epidemiology status of these new emerging Cryptosporidium species and genotypes in humans.