Research progress on small cell lung cancer with syndrome of inappropriate secretion of antidiuretic hormone
10.3969/j.issn.1000-8179.2017.05.364
- VernacularTitle:小细胞肺癌合并抗利尿激素分泌异常综合征的研究进展
- Author:
Pingping SUN
;
Xu WANG
- Keywords:
SCLC;
SIADH;
hyponatremia
- From:
Chinese Journal of Clinical Oncology
2017;44(5):233-237
- CountryChina
- Language:Chinese
-
Abstract:
Many malignant tumors, most commonly small cell lung cancer, merge with syndrome of inappropriate secretion of antidi-uretic hormone (SIADH). SIADH is caused by the neuroendocrine function of tumor cells or is a side effect of chemotherapeutics. As a chemotherapeutic side effect, SIADH presents as hyponatremia. Therapy for SIADH includes both treatment for primary diseases and hyponatremia. Given that SIADH-induced hyponatremia aggravates the prognosis and shortens the survival time of patients with malig-nant tumors, SIADH is an independent risk factor for prognosis. Therefore, the early diagnosis, monitoring, and treatment of SIADH will improve the prognosis of patients with malignant tumors.
