Advances in antiangiogenic drug-induced hypertension
10.3969/j.issn.1000-8179.2017.05.395
- VernacularTitle:抗血管生成靶向药物相关性高血压的研究进展
- Author:
Lina XIA
;
Long WANG
;
Houshen LI
- Keywords:
antiangiogenic drugs;
hypertension;
adverse effects;
tumor
- From:
Chinese Journal of Clinical Oncology
2017;44(5):238-245
- CountryChina
- Language:Chinese
-
Abstract:
Antiangiogenic therapy is an essential approach in the treatment of malignant tumors along with the development of preci-sion medicine. However, the occurrence of antiangiogenic therapy-induced hypertension, which is the most common toxicity of this agent, influences its broad clinical use (in some cases). Researches on its mechanisms, prevention, and management, have been con-ducted, but clinical guidelines or expert consensuses have not been reached. In this review, we presented the epidemiology, current re-search status, and systematic management of antiangiogenic therapy-induced hypertension.