Time-invariant CTA assessment of collateral circulation of patients with acute ischemic stroke
10.3969/j.issn.1002-1671.2017.03.011
- VernacularTitle:非时变CTA在急性脑梗死患者脑侧支循环的应用研究
- Author:
Xuehua WEN
;
Zhongxiang DING
;
Yumei LI
;
Jianhua YUAN
;
Xiangyang GONG
- Keywords:
cerebral infarction;
perfusion imaging;
angiography;
collateral circulation
- From:
Journal of Practical Radiology
2017;33(3):365-368
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of time-invariant CTA in assessing collateral circulation of patients with acute ischemic stroke and assisting clinicians in predicting clinical outcomes.Methods The score of collateral circulation was compared between single-phase and time-invariant CTA.NIHSS score was calculated at admission and two weeks after admission.A 50% or greater decrease in NIHSS score over two weeks was considered as major neurologic improvement,which showed good clinical outcome;otherwise,it indicated bad outcome.The predictive ability of time-invariant CTA for clinical outcomes was assessed based on ROC curves.Results Compared with single-phase CTA,more collateral vessels could be viewed on time-invariant CTA.The average score of collateral circulation on time-invariant and single-phase CTA was 1.50±0.69 and 1.15±0.49 respectively (P=0.006<0.05 ).Time-invariant CTA had the moderate predictive ability for clinical outcomes in patients with acute ischemic stroke (AUC=0.810;P=0.032<0.05). Conclusion The time-invariant CTA showed potential value in assessing collateral circulation of patients with acute ischemic stroke and assisting clinicians in predicting clinical outcomes.