A controlled study of hemodialysis combined with hemoperfusion for the treatment of microinflammation in diabetic nephropathy

VernacularTitle:血液透析与血液灌流疗法改善糖尿病肾病透析者微炎症状态的作用
Author: Ling MA ; Peng YUN
Keywords: diabetic nephropathy; renal dialysis; hemoperfusion; inflammation
From: Chongqing Medicine 2017;46(6):767-769
CountryChina
Language:Chinese
Abstract: Objective The aim of this study was to assess the effect of hemodialysis combined with hemoperfusion for the treatment of microinflammation in diabetic nephropathy patients.Methods One hundred and twenty-five cases of diabetic nephropathy experienced treatment from July 2014 to December 2015 in author's hospital were analyzed retrospectively.They were divided into two groups randomly.The observation group received hemodialysis combined with hemoperfusion,and the control group received just hemodialysis therapy.The status of microinflammation and curative effect were compared.Results The effective rate of observation group was 60.6％,while was 45.8％ in control group (P＜0.05).Microinflammation level:compared with control group,SAA,IL-6,IL-17,IL-22,IL-1β,TNF-αand TGF-β1 status of observation group showed decreased trend (P＜0.01).Conclusion Hemodialysis combined with hemoperfusion can effectively decreased microinflammation status in diabetic nephropathy.