Current Status of microRNA in tumor therapy
10.3969/j.issn.1005-1678.2017.03.098
- VernacularTitle:microRNAs在肿瘤治疗中的研究现状
- Author:
Junli DONG
;
Jianmin LIU
- Keywords:
microRNA;
tumor;
biomarker;
targeted therapy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):316-319
- CountryChina
- Language:Chinese
-
Abstract:
microRNAs is a class of non-coding RNA, which is the transcriptional regulator of gene expression at the post transcriptional level.These endogenous non-coding RNA are expressed abnormally in tumor cells, in the tumor cell growth, reproduction, apoptosis and metastasis and other processes play an important regulatory role.Recently, microRNAs was widely regarded as biological diagnostic and prognostic markers of tumor in clinic, has been widely viewed.This article will introduce the important role of miRNA in tumor gene expression, as well as the use of miRNA as a tumor targeted therapy clinical application before the need to solve the problem .
