Effect of Danshao Shugan granule combined with metformin in treatment of nonalcoholic fatty liver and its effects on lipid and uric acid metabolism
10.3969/j.issn.1005-1678.2017.03.030
- VernacularTitle:丹芍疏肝颗粒联合二甲双胍对非酒精性脂肪肝患者糖、脂、尿酸代谢的影响
- Author:
Xianxia MA
;
Jianping CHU
;
Qi JIANG
- Keywords:
Danshao shugan granule;
metformin;
nonalcoholic fatty liver;
blood uric acid;
insulin resistance
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):104-106
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of danshao shugan granule combined with metformin in treatment of nonalcoholic fatty liver and its effects on lipid and uric acid metabolism.Methods 80 patients of nonalcoholic fatty liver who received therapy from February 2014 to February 2015 in our hospital were selected as research objects.According to random number table,those patients were divided into the observation group (n=40) cases in each group and the control group (n=40).The control group was treated with metformin, while the observation group was treated with danshao shugan granule combined with metformin.Then blood lipid level, FBG, FINS, IR, SUA level, SOD, MDA level, therapeutic effect of two groups after treatment were compared.Results After treatment, TG,TC in observation group was significantly less than the control group (P<0.05); FBG, FINS, IR, SUA levels in the observation group were significantly lower than the control group ( P<0.05 ); SOD level higher than the control group, MDA level significantly less than the control group (P<0.05); The total effective rate of observation group was statistically higher than that in the control group (P<0.05).Conclusion Danshao shugan granule combined with metformin is well for nonalcoholic fatty liver,which can improve the glucose, lipid, uric acid metabolism and insulin resistance, and can protect the liver function.
