Effect of Bairui capsule combined with azithromycin in the treatment of mycoplasma pneumonia and its effect on serum hs-CRP, EC and SIL-2R
10.3969/j.issn.1005-1678.2017.03.038
- VernacularTitle:百蕊胶囊联合阿奇霉素治疗支原体肺炎的疗效及对患儿血清hs-CRP、EC、SIL-2R的影响
- Author:
Wentao JIANG
;
Yasu CHU
;
Jian WANG
- Keywords:
Bairui capsule;
azithromycin;
mcoplasma pneumonia;
high sensitive C-reactive protein;
eosinophil;
soluble interleukin-2
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):128-130
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the curative effect of Bairui capsule combined with azithromycin in treatment of children with mycoplasmal pneumonia and its effect on serum high sensitive C-reactive protein, eosinophil, soluble interleukin-2.Methods 86 patients with mycoplasma pneumonia were enrolled from August 2015 to July 2016 in our hospital.According to the order of admission, the patients were divided into observation group and control group.The control group was treated with azithromycin , and the observation group was treated with Bairui capsule and azithromycin.Clinical efficacy,symptoms and signs of disappearance of time, CRP, EC, SIL-2R and adverse reaction rate were compared between the two groups.Results The total effective rate in the observation group was significantly higher than the control group [90.70% (39/43) vs 67.44% (29/43)](P<0.05).The time of disappearance of lung rales, the disappearance time of cough, the time of fever and the recovery time of X -ray in the observation group were significantly shorter than the control group (P<0.05).The levels of serum hs-CRP, EC and SIL-2R in the observation group were lower than the control group (P<0.05) .There was no significant difference in adverse reaction rate between observation group and control group.Conclusion Bai Rui capsule combined with azithromycin in children with mycoplasma pneumonia can effectively reduce the serum hs-CRP, EC, SIL-2R levels, clinical efficacy is good, low adverse reaction rate.
