Primary Cutaneous CD30 (Ki-1) Positive Lymphoproliferative Disorder: Report of a Borderline Case.
- Author:
Nark Kyoung RHO
1
;
Seong Jae YOUN
;
Hyung Seok PARK
;
Eil Soo LEE
Author Information
1. Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. eslee@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Primary cutaneous CD30 positive lymphoproliferative disorder;
Lymphomatoid papulosis
- MeSH:
Drug Therapy;
Lymphoma;
Lymphoma, T-Cell, Cutaneous;
Lymphomatoid Papulosis;
Lymphoproliferative Disorders*;
Prognosis;
Recurrence;
Skin
- From:Korean Journal of Dermatology
2003;41(6):826-829
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary cutaneous CD30 positive large cell lymphoma is a cutaneous T-cell lymphoma with a favorable prognosis, which is characterized by solitary or localized skin lesions with a tendency of spontaneous regression and frequent relapses. On the basis of the morphologic and immunophenotypic similarities between the large atypical cells in lymphomatoid papulosis and the neoplastic cells in primary cutaneous CD30 positive large cell lymphoma as well as their favorable prognosis, these two diseases are now regarded to be in a spectrum of primary cutaneous CD30 positive lymphoproliferative disorder. We present a borderline case of primary cutaneous CD30 positive lymphoproliferative disorder which recurred on the anatomic site different to the primary lesions despite multiple-agent chemotherapy.