Clinical analysis of 15 patients with thrombotic microangiopathy induced by malignant hypertension

VernacularTitle:恶性高血压病引起的血栓性微血管病15例临床分析
Author: Jing YU ; Hui XIONG
Keywords: Malignant hypertension; Thrombotic microangiopathy
From: Chinese Journal of Interventional Cardiology 2017;25(2):102-106
CountryChina
Language:Chinese
Abstract: Objective To explore clinical characteristics and treatment of the thrombotic microangiopathy (TMA) induced by malignant hypertension, and provide a better understanding of the disease. Methods The clinical manifestations, laboratory examinations, therapeutic methods and prognosis of 15 TMA patients induced by malignant hypertension were analyzed retrospectively. Results The clinical manifestations were characterized by microangiopathic hemolytic anemia, thrombocytopenia and kidney injury. None of the patients required plasma exchange therapy. After antihypertensive treatment, all of 15 patients were discharged with improved clinical condition, remoglobin levels and platelet count. Conclusions The TMA induced by malignant hypertension is different from the classic TMA. Improving the understanding of TMA induced by malignant hypertension will contribute to early diagnosis and targeted treatment.