Influence of Zoledronic Acid Injection on Body Temperature of Patients with Primary Osteoporosis
10.3870/j.issn.1004-0781.2017.02.024
- VernacularTitle:唑来膦酸注射液对原发性骨质疏松患者体温的影响
- Author:
Chunyan ZHANG
;
Xiaolei REN
;
Haiying ZHANG
;
Bin ZHANG
;
Wanyu FENG
- Keywords:
Zoledronic acid injection;
Body temperature;
Prophylactic use
- From:
Herald of Medicine
2017;36(2):213-215
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of zoledronic acid injection on body temperature of patients with primary osteoporosis.Methods A total of 142 patients with primary osteoporosis who received intravenous zoledronic acid treatment in Peking university people's hospital during 2013-2014 were enrolled in this study.The body temperature before and after intravenous zoledronic acid treatment were recorded and analyzed with SPSS 17.0 software.Results The patients'body temperature at different time points after intravenous zoledronic acid treatment was significantly different (P =0.000).Prophylactic use of NSAIDs could significantly reduce patients' body temperature at the second day after intravenous zoledronic acid.Conclusion NSAIDs can be given orally on the same day of intravenous injection of zoledronic acid,and continued for three days.
