Histomorphometric evaluation of ridge preservation after molar tooth extraction
10.3969/j.issn.1671-167X.2017.01.031
- VernacularTitle:罹患重度牙周炎磨牙拔除后应用去蛋白牛骨基质与可吸收胶原膜进行位点保存的组织学研究
- Author:
Yalin ZHAN
;
Wenjie HU
;
Tao XU
;
Min ZHEN
;
Ruifang LU
- Keywords:
Periodontitis;
Guided tissue regeneration,periodontal;
Alveolar ridge augmentation;
Biocompatible materials;
Histology
- From:
Journal of Peking University(Health Sciences)
2017;49(1):169-175
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate bone formation in human extraction sockets with absorbed surrounding walls augmented with Bio-Oss(R) and Bio-Gide(R) after a 6-month healing period by histologic and histomorphometric analyses.Methods:Six fresh molar tooth extraction sockets in 6 patients who required periodontally compromised moral tooth extraction were included in this study.The six fresh extraction sockets were grafted with Bio-Oss(R) particle covered with Bio-Gide(R).The 2.8 mm × 6.0 mm cylindric bone specimens were taken from the graft sites with aid of stent 6 months after the surgery.Histologic and histomorphometric analyses were performed.Results:The histological results showed Bio-0ss(R) particles were easily distinguished from the newly formed bone,small amounts of new bone were formed among the Bio-Oss(R) particles,large amounts of connective tissue were found.Intimate contact between the newly formed bone and the small part of Bio-Oss(R) particles was present.All the biopsy cylinders measurement demonstrated a high inter-individual variability in the percentage of the bone,connective tissues and BioOss(R) particles.The new bone occupied 11.54% (0-28.40%) of the total area;the connective tissues were 53.42% (34.08%-74.59%) and the Bio-Oss(R) particles were 35.04% (13.92%-50.87%).The percentage of the particles,which were in contact with bone tissues,amounted to 20.13% (0-48.50%).Conclusion:Sites grafted with Bio-Oss(R) particles covered with Bio-Gide(R) were comprised of connective tissues and small amounts of newly formed bone surrounding the graft particles.