Analysis of the change of vaginal microenvironment in pregnant women with preterm premature rupture of ;the membranes
10.3760/cma.j.issn.1008-6706.2017.02.012
- VernacularTitle:未足月胎膜早破孕妇阴道微环境变化情况分析
- Author:
Bangwu CHEN
;
Jiuqiong HU
- Keywords:
Fetal membranes,premature rupture;
Vaginal;
Lactic acid bacteria;
Immunologic factors
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):205-208
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the vaginal microenvironment in pregnant women with preterm premature rupture of the membranes,and to explore the change of vaginal microenvironment in pregnant women with preterm premature rupture of the membranes.Methods 1 16 women with preterm premature rupture of the membranes were selected as preterm premature rupture of the membranes group,1 16 women with normal pregnancy outcomes were selected as control group.The vaginal pH value,vaginal lactobacilli,vaginal sialidase and HD5,IgE and SIgA levels were observed.Results At 28 weeks of pregnancy,the vaginal PH value,sialidase detection rate and HD5,IgE,SIgA levels of preterm premature rupture of the membranes group were higher than those of the control group,but there were no significant differences between the two groups(t=1.037,χ2 =1.052,t=1.282,1.051,1.861,all P>0.05).At pregnant 36 weeks,the vaginal pH value,sialidase detection rate and HD5,IgE,SIgA levels of preterm premature rupture of the membranes group[(4.13 ±0.22),71.4%,(12.53 ±1.55)pg/mL,(338.84 ±1.67)ng/mL, (53.44 ±1.57)μg/mL]were higher than those of the control group[(3.79 ±0.25),13.8%,(8.77 ±3.17)pg/mL, (167.43 ±3.66)ng/mL,(37.59 ±1.85)μg/mL],the differences were statistically significant(t=12.331,χ2 =24.816,t=5.258,9.469,7.357,all P<0.05).At 28 weeks of pregnancy,the vaginal lactobacilli detection rate of preterm premature rupture of the membranes group was lower than that of control group,but there was no significant difference(χ2 =1.723,P>0.05).At 36 weeks gestation,the vaginal lactobacilli detection rate of preterm premature rupture of the membranes group was lower than that of the control group,the difference was statistically significant (χ2 =19.545,P<0.05).Conclusion Preterm premature rupture of the membranes pregnant vaginal pH value increases,the detection rate of vaginal lactobacilli decreases,vaginal sialidase detection rate increases,vaginal immune factors HD5,IgE,SIgA level increases.
