Analysis of the clinical curative effect of neural endoscopic nasal adjustment surgical treatment for pituitary ;adenomas
10.3760/cma.j.issn.1008-6706.2017.02.014
- VernacularTitle:神经内镜下经鼻蝶手术治疗垂体腺瘤的临床疗效
- Author:
Honggang REN
- Keywords:
Prolactinoma;
Neuroendoscopy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical curative effect of neural endoscopic nasal adjustment surgical treatment for pituitary adenomas.Methods The clinical data of 176 patients with pituitary adenoma were retrospec-tively analyzed.82 patients in group A used microscopic surgery treatment,94 cases were treated by nerve endoscopic treatment(group B).The operation time,postoperative hospital stay time,the cutting rate,hormone levels,recovery rate and complications were compared between the two groups.Results In group A,the operation time,postoperative hospitalization time,the whole cut were (103.5 ±21.5)min,(7.8 ±1.1)d,78 cases,those of group B were (109.1 ±25.8)min,(5.2 ±1.0)d,91 cases,the operation time,whole cut of the two groups had no statistically significant differences(t=1 .55 1 ,χ2 =0.034,all P>0.05 ).The postoperative hospitalization time of group A was longer than that of group B,the difference was statistically significant(t=16.422,P<0.01 ).Postoperative hormone level recovery rate was similar between the two groups,there was no statistically significant difference(χ2 =0.010, P>0.05).In group A,the transient diabetes insipidus,nasal symptoms,complications were higher than those in the control group,the differences were statistically significant(χ2 =10.746,P <0.01,χ2 =5.146,P <0.05).The cerebrospinal fluid leak,low pituitary function,intracranial hematoma,intracranial infection,the incidence of visual impairment aggravating were similar between the two groups,there were no statistically significant differences (all P>0.05 ).Conclusion Neural endoscopic nasal adjustment of surgical treatment of pituitary adenoma and the microscopic surgery has similar clinical curative effect,but has a lower incidence of complications and shorter postop-erative hospital stay.