Clinical Observation for Treatment of Perimenopause Hypertension by Qianyang Mixture
10.3969/j.issn.1005-5304.2017.02.006
- VernacularTitle:潜阳合剂治疗围绝经期高血压临床观察
- Author:
Yvsup ZULHUMAR
;
Liya MA
;
Wei GUO
;
Yongming LIU
- Keywords:
perimenopause hypertension;
Qianyang Mixture;
clinical observation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(2):17-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Qianyang Mixture for the treatment of perimenopause hypertension. Methods Eighty cases of perimenopause hypertension patients were randomly divided into treatment group and control group, with 40 cases in each group. The two groups were given Amlodipine Besylate Tablets for oral taking, one tablet each time, once a day. The treatment group was treated with Qianyang Mixture, 35 mL for each time, twice a day, 1 h after meal. Course of treatment was 12 weeks. The changes of blood pressure, heart rate and sex hormone level of patients in both groups were observed, and efficacy of TCM syndrome were evaluated. Results After treatment, the heart rate, average daily blood pressure and morning blood pressure of the treatment group were lower than those of the control group, with statistical significance (P<0.05);After the treatment, the levels of estradiol in the treatment group were higher than those in the control group, with statistical significance (P<0.05). The total effective rate was 92.5% (37/40) in the treatment group and 80.0% (32/40) in the control group, with statistical significance (P<0.05). Conclusion Qianyang Mixture can obviously reduce blood pressure and heart rate of patients with perimenopause hypertension, and can regulate hormone levels, improve TCM symptoms.
