Clinical Study on Treatment of Diabetic Gastroparesis on Self-designed Xiaopi Formula
10.3969/j.issn.1005-5304.2017.02.008
- VernacularTitle:自拟消痞方治疗糖尿病胃轻瘫临床研究
- Author:
Yue ZHANG
;
Yan DONG
;
Qian WANG
;
Jing ZHOU
;
Yuqing YANG
;
Yuanyuan ZHANG
;
Lili YAN
;
Yinglai ZHANG
;
Zhi LIU
- Keywords:
diabetes mellitus;
gastroparesis;
self-designed Xiaopi Formula;
efficacy evaluation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(2):25-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy on the treatment of diabetic gastroparesis of self-designed Xiaopi Formula. Methods Totally 200 cases of DGP were divided into the observation group and the control group with random number table, with 100 cases in each group. Two groups were given the general treatment scheme, such as the subcutaneous injections of insulin or oral hypoglycemic medicine. The patients in the control group were treated with Domperidone orally, one tablet each time, 3 times a day;while the patients in the observation group were treated with self-designed Xiaopi Formula, twice a day, one time for morning and one time for evening. One course lasted for one month, 3 courses in total. Clinical efficacy and the change of gastric emptying rate, glycosylated hemoglobin and hemorrheology in the two groups were observed. Results Total effective rate of observation group (94.0%) was higher than that of the control group (82.0%), with statistical significance (P<0.05). After treatment, blood sugar decreased and gastric emptying rate improved in both groups (P<0.05), and observation group was superior to control group (P<0.05); The control group in terms of improving hemorrheology had no obvious significance (P>0.05); Observation group can obviously improve the indexes of blood rheology, with statistical significance with control group (P<0.05). Conclusion The clinical efficacy of self-designed Xiaopi Formula for the treatment of diabetic gastroparesis is obvious, which can promote gastric emptying rate and decrease HbA1c level, and improve blood rheology.
