Effect of Shenkangling on Inflammatory State and Residual Renal Function in Patients with ;Maintenance Hemodialysis
10.3969/j.issn.1005-5304.2017.02.011
- VernacularTitle:肾康灵对维持性血液透析患者炎症状态及残余肾功能的影响
- Author:
Zhi ZHANG
;
Hongjuan LIANG
;
Jisheng WANG
- Keywords:
dialysis;
Shenkangling;
renal function;
inflammation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(2):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the inflammatory state and residual renal function (RRF) of the patients with maintenance hemodialysis treated through Shenkangling. Methods Sixty patients with maintenance hemodialysis were randomly divided into two groups, the observation group (30 cases) and the control group (30 cases). They were treated through hemodialysis and hemodiafiltration. The patients in the observation group were treated with Shenkangling 8 tablets/time, 3 times/day. RRF and urine volume after six months were evalued. Serum high-sensitivity C reactive protein (hs-CRP), tumor necrosis factor alpha (TNF-α), and leukocyte mediated IL-6 (IL-6) before and after treatment were detected. Results There were no statistical differences in RRF and urine volume between the two groups before treatment (P>0.05). After six months, RRF and urine volume in the two groups were significantly reduced (P<0.05), and those of the observation group were significantly higher than those of the control group (P<0.05). There was no statistical significance in serum hs-CRP, TNF-α and IL-6 between the two groups before treatment (P>0.05). After treatment, the serum levels of hs-CRP, TNF-α, IL-6 significantly decreased in the observation group, and lower than those of the control group (P<0.05). Conclusion Shenkangling can protect the residual renal function of hemodialysis patients, and reduce the inflammatory reaction.
