Effect of atorvastatin on postoperative complications after the burr hole drainage of chronic subdural hematoma
10.3760/cma.j.jssn.1673-4904.2017.01.016
- VernacularTitle:阿托伐他汀对于慢性硬脑膜下血肿钻孔引流术后并发症的影响
- Author:
Wenfu HU
;
Jun LI
;
Fei YANG
;
Jiahe SUN
;
Yicheng SONG
- Keywords:
Hematoma,subdural,chronic;
Drainage;
Postoperative complications;
Atorvastatin
- From:
Chinese Journal of Postgraduates of Medicine
2017;40(1):56-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of atorvastatin on postoperative complications after the burr hole drainage of chronic subdural hematoma (CSDH). Methods The clinical data of 172 CSDH patients who had underwent the burr hole drainage were retrospectively analyzed. Among them 82 patients were given atorvastatin (atorvastatin group), and 90 patients were not given atorvastatin (control group). The postoperative complications were compared between 2 groups. Results All patients were followed up for 6 months. The total incidence of postoperative complications in control group was significantly higher than that in atorvastatin group:47.78%(43/90) vs. 31.71%(26/82), and the recurrent rate of subdural hematoma and incidence of subdural effusion in control group were significantly higher than those in atorvastatin group: 22.22% (20/90) vs. 8.54% (7/82) and 28.89% (26/90) vs. 12.20%(10/82). There were statistical differences (P<0.05). There were no statistical difference in the incidences of pneumocephalus, acute epidural/subdural hematoma and brain damage induced by drainage tube (P>0.05). Conclusions Atorvastatin can improve the prognosis of CSDH patients, especially in reducing the incidence of recurrent subdural hematoms and subdural effusion.
