Research progress of different cells derived exosomes in atherosclerosis
10.3969/j.issn.1001-1978.2017.01.006
- VernacularTitle:不同细胞来源的外泌体在动脉粥样硬化中的研究进展
- Author:
Chao LI
;
Min DAI
- Keywords:
exosomes;
extracellular vesicles;
atherosclerosis;
cells;
inflammation;
immunity;
miRNAs
- From:
Chinese Pharmacological Bulletin
2017;33(1):27-32
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are nanosized membrane particles secreted by cells that transmit information from cell to cell.Exosomes in-volve in the regulation of important physiological activities of cells and play an important role in the formation and develop-ment of atherosclerosis (AS ).As one of extracellular vesicles, exosomes is getting increasingly attention.This article aims to review the role of exosomes derived from the AS related cells (immune cells,platelets,vascular endothelial cells,vascular smooth muscle cells)in the pathogenesis of AS.