Chemotherapy in Breast Cancer.
10.12771/emj.2014.37.2.75
- Author:
Anbok LEE
1
;
Byung In MOON
Author Information
1. Department of Surgery, Ewha Womans University School of Medicine, Seoul, Korea. mbit@ewha.ac.kr
- Publication Type:Review
- Keywords:
Breast neoplasms;
Chemotherapy
- MeSH:
Breast Neoplasms*;
Drug Therapy*;
Drug Therapy, Combination;
Female;
Humans;
Incidence;
Mortality
- From:The Ewha Medical Journal
2014;37(2):75-82
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Breast cancer is the second most common cancer in Korean women and its incidence has increased. Among the various treatment methods for breast cancer, chemotherapy plays an important role. The use chemotherapy to treat breast cancer began at the mid 20th century and first combination chemotherapy was conducted in mid 1970s. This chemotherapy reduced breast cancer mortality up to 25~30%, anthracycline and taxane based chemotherapeutic regimens are widely used. Chemotherapy could be classified to neoadjuavnt, adjuvant and palliative setting according to its aim and role. In this review, various drug therapeutic options and their backgrounds are considered based on neoadjuvant, adjuvant and metastatic systemic therapies.
