Cytomegalovirus Colitis with Colon Perforation and Lower Gastrointestinal Bleeding in a Immunocompetent Patient.
10.12771/emj.2014.37.2.105
- Author:
Sun Wook KIM
1
;
Yoon Jin CHA
;
Min Hwan KIM
;
Moo Nyun JIN
;
Jung Hee LEE
;
Hye Jung PARK
;
Sooyun CHANG
;
Hyuk LEE
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Colitis;
Immunocompetence
- MeSH:
Adult;
Colitis*;
Colon*;
Colon, Transverse;
Colonoscopy;
Cytomegalovirus*;
Ganciclovir;
Hemorrhage*;
Humans;
Immunocompetence;
Immunocompromised Host;
Immunohistochemistry;
Male;
Mortality;
Ulcer
- From:The Ewha Medical Journal
2014;37(2):105-108
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) infection in immunocompromised patients is associated with significant morbidity, mortality, and adverse clinical outcome. However, CMV infection in immunocompetent patients has been considered to have subclinical and self-limited course, and does not require treatment. We reports a case of CMV colitis, presented with colon perforation and lower gastrointestinal bleeding in a immunocompetent 31-year-old young male. After conservative treatment, colonoscopy revealed multiple ulcers in transverse colon. CMV colitis was confirmed by microscopic findings and immunohistochemistry. After successful treatment with ganciclovir, the patient improved without invasive procedure.
