The relationship between vaccination and febrile seizure、GEFS+ and Dravet syndrome
10.3760/cma.j.issn.1673-4408.2016.12.004
- VernacularTitle:热性惊厥、GEFS＋、Dravet综合征与疫苗接种的关系
- Author:
Li YANG
;
Fei YIN
- Keywords:
Febrile seizure;
GEFS+;
Dravet syndrome;
Vaccination
- From:
International Journal of Pediatrics
2016;43(12):916-919
- CountryChina
- Language:Chinese
-
Abstract:
Vaccination in children suffering neurological diseases is a troublesome issue that people es-pecially pediatricians are reluctant to mention. Due to worrying about the emergence of adverse reactions and concerning on the heat induced seizure,doctors and parents tend to cancel or do not recommend these children to be vaccinated. Additionally,the heat sensitive seizures,such as febrile seizure( FS) ,generalized epilepsy with fe-brile seizure plus(GEFS+),Dravet syndrome account for the largest proportion of the seizure related disease and epilepsy syndrome. Their pathogenesis has been proved relating to the mutation of SCN gene of the sodium channel. For children with FS,GEFS+,and Dravet syndrome,vaccination may lead to fever,which even may bring about convulsions,but it will not result in worse prognosis.
