Role of brain -derived neurotrophic factor in pathological mechanism of autism spectrum disorder
10.3760/cma.j.issn.2095-428X.2016.24.019
- VernacularTitle:脑源性神经营养因子在孤独症谱系障碍发病机制中的作用
- Author:
Zhen ZHENG
;
Yi QU
;
Dezhi MU
- Keywords:
Brain -derived neurotrophic factor;
Autism spectrum disorder;
Pathological mechanism
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(24):1912-1914
- CountryChina
- Language:Chinese
-
Abstract:
The brain -derived neurotrophic factor (BDNF)plays an important role in the development and function of the nervous system.BDNF controls the neuronal survival,differentiation,growth of dendrites and axons,for-mation of synapse,neuronal plasticity and the basic process of learning and memory through a variety of ways,the dys-regulation of which is probably the important molecular mechanism responsible for the onset of autism spectrum disor-der.The research advance on preclinical research and clinical research between BDNF and autism spectrum disorder is reviewed in this paper.
