Clinical research progress of presepsin on sepsis
10.3760/cma.j.issn.1673-4912.2016.12.011
- VernacularTitle:可溶性白细胞分化抗原14亚型在脓毒症中的研究进展
- Author:
Wenjuan ZHENG
;
Jianxin WU
;
Xiaoxu REN
;
Yimin ZHU
- Keywords:
Sepsis;
Presepsin;
Procalcitonin
- From:
Chinese Pediatric Emergency Medicine
2016;23(12):846-851
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a frequent condition with high mortality,and its early diagnosis in the pediatrics department is one of the keys to improve survival. C-reactive protein and procalcitonin have been used as bio-markers in the diagnosis of sepsis,but they have limited susceptibility and specificity,and can be elevated in non inflammatory condition. Presepsin is the free fragment of a glycoprotein expressed on monocytes/macro-phages. Preliminiary reports suggest that levels of presepsin are significantly higher in septic patients com-pared to healthy individuals, and presepsin is useful for evaluating the severity of sepsis.
